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Comparison of same areas of same object with pictures took in different times

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Comparison of same areas of same object with pictures took in different times

humblebee
1 post
Dear members,
As in the title, I need to follow the changes of an object with consequential taken pictures.
I need to focus on small details, so it would be great if the program could point out these ones automatically orienting itself with ROI on the image.
Maybe I'll be more clear with an example:
I need to follow the evolution of some bacterial colonies (not all the colonies) on an agar plate,I put some marks on the agar (two or three coloured pieces of paper) so the software can underline which colonies I have to check orienting the picture with the help of the marks.
Does anybody know a plugin to do this?
Thanks in advance!