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hacking help, please

Posted by Kenneth Sloan-2 on Sep 01, 2010; 3:27am
URL: http://imagej.273.s1.nabble.com/hacking-help-please-tp3687063.html

I would appreciate pointers, clues, and hints on how to do the following:

a) outline a large, blob-like region in an image
b) within that region, outline MANY small included regions
c) report:
        for the large blob: area
        for EACH small included blob:
                centroid
                area
                integrated intensity
d) subtract all of the included blobs from the large blob, and then report:
        remaining area
        integrated intensity over that area

I can see most of the pieces by pointing and clicking and reading the manual - but it would really help
to see something close to an actual implementation.

My immediate stumbling blocks are:
        * displaying the enclosing blob boundary AND the boundaries of all the smaller blobs
          (my problem is that I can only see the current blob - which then disappears when I start on the next one)
        * details on managing the results

I'm probably more comfortable writing Java code - but I'd be happy to try to do this as a macro.

I'll probably want to use a polygon for the large blob boundary - and fit ellipses to the smaller blobs.

If you care - what I'm measuring are cone inner segments in human retina and mitochondria.  (actually, someone else will sit
at the image and count them - I'm the GUI guy).

To calibrate - I've been creating systems to help people make these sorts of measurements for some 30+ years, and am comfortable writing fairly complicated pieces of Java code - what I need help on are the nitty gritty details.

(perhaps all I need are pointers of the form: "check out tutorial #'s 3, 5, 11, and 43")

Thanks very much - all clues gratefully accepted.  

With luck, I can demo the resulting system, and show off some results, in Luxembourg.

--
Kenneth Sloan
[hidden email]