Posted by
Ricardo Henriques-2 on
Jul 08, 2009; 3:33pm
URL: http://imagej.273.s1.nabble.com/Call-for-PhD-students-or-Post-Docs-in-Wave-Front-Engineering-Super-resolution-Imaging-and-Visual-Basg-tp3691870.html
Call for PhD students or Post-Docs in Wave Front Engineering, Super-
resolution Imaging and Visual Based High-Content Screening:
The Gene expression and Biophysics Unit at CSIR-Synthetic Biology is
looking for
a number of highly motivated persons with training in biological
sciences,
engineering, computer sciences and experimental optics.
Our international newly created group is interested in developing novel
technologies in microscopy that range from artificial intelligence in
image
acquisition, stochastic super-resolution quantitative methods and
visual based
high content screening. We also are actively involved in training
students in
imaging and microscopy through training workshops see:
http://microscopy.synbio.csir.co.zaOpen projects and positions:
Adaptive Sampling Microscopy and Wave Front Engineering (1 or 2
positions
preferably Post doc):
Recently microscopy as been able to become parallel with Moore's law,
technology developments have allowed us to achieve single molecule
imaging in
living cells and a macro-to-nano overview of how biology works.
Although these
amazing features can be achieved, most decisions based on hardware
control are
still carried out by humans. This project aims to create data driven
computer
assisted or artificial intelligence based microscope hardware control
with the goal
of creating an imaging system with optimal performance able to adapt
to sample
characteristics and through it minimize sample damage.
The candidate will be in charge of:
−Developing novel light microscopy set-ups able to spatially adapt
the excitation
illumination, sampling and sample environment
−Implement and develop new data driven microscope control and analysis
methods
Dynamic Resolution in High Content Screening (2 positions preferably
post doc):
Through high content screening microscopy, it is possible to overview
the
dynamic behavior of a large population of cells. This project aims to
merge this
technique with super-resolution light microscopy (PALM and STORM) by
creating
a dynamic decision scheme where the microscope creates a low
magnification
survey of target events that will trigger the super-resolution imaging
of regions of
interest. Especially in genome-wide approaches, such as siRNA screens.
The candidate will be in charge of:
−Developing image analysis, image quantification and hardware control
methods
−Developing imaging assays amenable to genome-wide screening
approaches,
and drug screening approaches.
What we expect from the candidate(s):
We expect a strong interest in learning new experimental techniques and
computational tools, and the ability to work in a highly collaborative
environment.
The following characteristics will be taken into account:
−Hands-On experience in Optical Microscopy
−Scientific programming in the languages Python or Matlab
−Basic knowledge of C, C++
−Experience in biology (preferable but not required)
−A keen interest in our research themes
−A true commitment to learn, explore, innovate & develop new skills
−A strong wish to share and synergize your expertise with all members
of the
group
We offer a position in a multi-disciplinary group and the possibility
to work with
state of the art microscopy hardware and data analysis resources like
the Blue
Gene cluster.
Research in our newly established and multi-national group spans the
disciplines
of "super" resolution imaging and image analysis/signal processing,
the study and
imaging of gene expression, the development of cell-based bioassays for
screening, and molecular genetics. Of particular interest are
candidates with
extensive and advanced training in biology as well as training in
electrical
engineering and automation/robotics.
What you should expect from us:
- Team work
- Acquire a profound understanding of Cellular Imaging,
Quantitative
Biology and High throughput biology
- Exposure and training in scientific writing, manuscript review
and editing,
and writing grant proposals
- Training in how to interpret, organise, present you data in
lab meetings,
seminars and international conferences. As well as extensive
international
exposure.
- Training to become independent
- Lots of hard work and fun
Candidates should be communicative, thoughtful scientists who are highly
motivated, have good communication skills (both written and verbal),
and have the
desire to work with a dynamic, multi-disciplinary and international
group. Interested
candidates should contact Dr. Musa Mhlanga,
[hidden email], for
more
information. The positions will remain open until they are filled.