http://imagej.273.s1.nabble.com/Zeiss-LSM-file-defeats-LSM-Reader-Toolbox-tp3697026p3697031.html
> Hi,
>
> I'm trying to read Zeiss LSM files directly into ImageJ rather than having
> to use the free Zeiss Image Browser software to export TIFFs first. These
> files are produced from linescan experiments (laser whizzes back and forth
> along a line, resulting in an image representing x vs time). There are two
> 12 bit channels, one for each wavelength used, and the resulting 'images'
> are subsequently ratioed to produce a single linescan image.
>
> Unfortunately, none of the available free software that I have tried so far
> seems to be able to handle these files. LSM Reader reports "Unsupported LSM
> scantype: 2", and if I rename the file from .LSM to .TIF, TiffDecoder tells
> me that "ImageJ cannot open 48-bit LZW compressed TIFFs".
>
> (I also tried the MATLAB function tiffread.m mentioned at
>
http://en.wikipedia.org/wiki/LSM_(Zeiss) but that didn't work either and
> in any case I really want to use ImageJ not MATLAB!)
>
> Would it be straightforward to modify LSM Reader to be able to handle these
> files? Presumably a LZW decoder is now included. Is it simply a matter of
> interpreting the resulting decompressed bytes as pairs of 12 bit chunks?
>
> Cheers,
> Francis