Re: counting cells

Posted by ctrueden on
URL: http://imagej.273.s1.nabble.com/counting-cells-tp5001091p5001100.html

Hi Thuraya,

> i need help how to count cells with the dark purple color that exist
> in the big circle area

Did you try Fiji's Color Threshold plugin? I tried it with your sample
image and got pretty good results with the following settings:

Hue: 186 - 216
Saturation: 0 - 255
Brightness: 0 - 180

You can then create a selection & mask and manipulate them in a variety of
ways:

- Click the Select button in the Threshold Color dialog to create a
selection.

- Run the following plugins (press L for command finder):
 -- Create Mask
 -- Fill Holes (on the binary image)
 -- Watershed (chops up blobs into convex shapes/cells)
 -- Analyze Particles... (on the binary image, same options as above)
  --- Size: 10-Infinity
  --- Display results
  --- Clear results
  --- Add to Manager
  --- Exclude on edges

Now you have your cells in the ROI Manager, so you can:

- Close Mask window (Don't save)
- Close Results window
- Finally, in ROI Manager window, check Show All and Labels boxes

Your original image will show the cell outlines. To measure them, run:

- Run "Set Measurements..." (to configure which statistics are calculated)
- Click "Measure" button in ROI Manager

Now your measurements will be based on the original data, using the ROIs
(cells) from the ROI Manager.

Here is a screenshot of the cells I segmented using the above procedure:

    http://code.imagej.net/curtis/fiji-particles.jpg

That was just a quick attempt (e.g. a few of the cells are fused, and there
are some overly-small cells). You can do better by tweaking further with
the Threshold Color settings, and using a bigger minimum Size (perhaps
"25-Infinity"?) in the Analyze Particles dialog.

You could also try CellProfiler (http://cellprofiler.org/); it has many
good techniques for this sort of thing.

Regards,
Curtis


On Mon, Dec 10, 2012 at 5:53 AM, Thuraya Medhat <[hidden email]>wrote:

> Hello everybody,
>
> i need help how to count cells with the dark purple color that exist in the
> big circle area
> please help me if you can
>
> here is the link for the image,
> http://imageshack.us/photo/my-images/834/46609221.jpg/
>
> --
> ImageJ mailing list: http://imagej.nih.gov/ij/list.html
>

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