Dear Daniel,
In case you are unaware of it, freesurfer is a powerful package designed for segmentation of normal brain anatomy.
Here's a link to the front page of their website.
https://surfer.nmr.mgh.harvard.edu/There's an active email list with an online archive.
It seems very likely that much about your problem has been solved by people on that list and the solutions may well be in the archive.
Best - Don
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From: ImageJ Interest Group <
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Sent: Tuesday, September 4, 2018 9:15 AM
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Subject: Re: How to segment a brain tumor?
These are the Images
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