image registration question

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image registration question

jay chen
Dear all:

          I would like to co-register microPET and MRI images.  The
dimensions of PET and MRI images are 256*256*63 (pixel
sizes:0.4226*0.4226*1.21) and 128*128*128 (pixel
sizes:0.3125*0.3125*0.3125) respectively.  To facilitate registration,
I am thinking to
1. reslice the dimensions to make both PET and MRI same dimensions
(but different pixel sizes)
2. adjust  pixel sizes to make both images same pixel sizes (but
different dimensions)
3. make both images same dimensions and pixel sizes
4. not change dimensions and pixel sizes and go ahead to do co-registration

       Could anyone tell me which way is better?  I really appreciate your help.

                                    Best Regards
                                    Jay Chen